Kiyoshi Shiga
In 1897, during a severe dysentery epidemic in Japan, bacteriologist Kiyoshi Shiga successfully isolated the causative organism from patients’ stool samples.
The epidemic occurred in Japan and caused over 90,000 cases with high mortality, making it a major public health crisis.
Shiga demonstrated that the bacterium produced a potent toxin (now called Shiga toxin), which plays a central role in the disease.
Kiyoshi Shiga = Shigella
Shigella = Shigellosis
Classification Of Shigella
Virulence Factors Of Shigella




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