28.04.2024: Home Invasion

 

                                Have Never Seen So Many Mosquitoes In My Room Before

                                                         Home Invasion Of Mosquitoes !!!!

Ornithine Transcarbamylase Deficiency

 

                                                                          Urea Cycle

 

 

 

Ornithine Transcarbamylase Deficiency = Increased Orotic Acid

 

 

 

 

 

 

 

 

OTC Deficiency = Hyperammonemia 

 

 

 

 

 

 

Snapshot

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Orotic Acid

 

                                                                               B 13

 

 

Orotic Acid was isolated in 1940s from distillers

 

Known As Vitamin B13 

 

 

 

Vitamin B13 = Pyrimidinecarboxylic Acid  

 

 

 

 

Orotic Acid: Intermediate In Biosynthesis Of Pyrimidines

 

 

 

Biosynthesis Of Pyrimidines  

 

 

 

 

 Disorders Of Pyrimidine Metabolism

 

 

 

 

Health Effects

 

 

 

Magnesium Orotate 

 

 

 

 

 

 

Snapshot

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Tetrahydrobiopterin

 

                                                                  Tetrahydrobiopterin

 

 

 

 

GTP Synthesis Takes Place Inside 

 

The Cytoplasm  Through Citric Acid Cycle 

GTP To Tetrahydrobiopterin

 

 

 

 

 

 

Tetrahydrobiopterin (BH4)

 

 

 

 

 

 

 

BH4 Pathology

 

Low BH4/ High BH4 

 

 

 

 

 

 

Theory To Practice

 

 

Snapshot  

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Octahedron

 

                                                                        Platonic Solids 

 

 

 Octahedron

 

 

 

 

 

 

Snapshot