Onion Layers Under A Microscope

 

 

 

 

 Peeling The Onion: Onion Has Layers 

 

1-2-3-4-5-6-7-8-.......................... 

 

 

 

 

 

 

 

Onion Layers Under A Microscope

 

 

 

 

 

 

 

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Question Mark Under A Microscope

 

                                                                

Leptospira interrogans

 

The name interrogans was given by Stimson in 1907 because the organism looked like a question mark (?) under a microscope. 

 

 

 

 

 

 

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Still's Disease

 

                                                                   Still aka Not Moving 

 

 

 

 

 

Still Makes You Ill

 

Dr Friedric Still 

 

 

• In 1897, English physician George Frederic Still described a form of chronic arthritis in children with fever, rash, and enlarged lymph nodes.

This condition became known as:

• Still’s disease
• Later called Juvenile rheumatoid arthritis
   
   

   

   

   

   

  Stills Disease aka Juvenile Idiopathic Arthritis 

   

  

   

  

  
   

  Pathophysiology Of Juvenile Idiopathic Arthritis 

  
  
  

  

  
  

  
  Current Events
   
  

  
   
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Neuroblastoma

 

In 1891, American pathologist James Homer Wright described a childhood adrenal tumor with characteristic circular cell arrangements now called Homer Wright rosettes.

 James Homer Wright proposed that these tumors arose from primitive sympathetic nerve cells (neuroblasts).

                                            James Homer Wright = Homer Wright Rosettes 

 

 

 

 Neuroblastome 

 

Cancer that arises from neural crest cells  

 

 

  Chromosomal abnormalities found in neuroblastoma 

• In the 1980s, amplification of the MYCN gene was discovered.

MYCN amplification became:

• Marker of aggressive disease
• Important prognostic factor  

• 1p deletion/17q gain/ALK mutation

   

  

 

 

 

MYCN And Tumour Biology 

 

 

 

 

 

 

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