Wednesday, 1 April 2026

Pox

 

Poxviruses belong to the family Poxviridae, a group of large, double-stranded DNA viruses that infect humans and animals. The most famous member is Variola virus, which causes smallpox. 


 The mummy of Ramesses V (d. ~1157 BCE) shows skin lesions consistent with smallpox.

 

 
 
Pox Virus - Molluscum Contagiosum
 
 
 
 
Henderson–Patterson bodies are characteristic inclusion bodies seen in infection with the Molluscum contagiosum virus, a member of the Poxviridae
 
  • First clearly described by:
    • F. G. Henderson
    • R. W. Patterson
  • 📅 Year: ~1905–1910 (early 20th century)
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    Hungry Bone Syndrome

     

                                                                    Hungry Bone Syndrome  

     
     Hungry Bone Syndrome 
     
    Seen In Parathyroidectomy  For Hyperparathyroidism
     
     
     
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    Angel Of Death

     

     
     
    Angel Of Death
     

     
    Exodus 12:29
     
     
    Azrael 
     
    Azrael is widely known as the Angel of Death in many religious traditions, especially in Islam, Judaism, and some Christian folklore. 
     
     
     
     
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    Morning Star

     
     
     
    Venus: Morning Star
     
     
     
    Venus: Morning Star
     
    Lucifer aka Latin Name For Venus 
     
        Lucifer aka Phosphorus  


     
     
     
     
    Morning Star In The Bible 
     

     
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    Methuselah Star

     

     
    Methuselah: Oldest Man In The Bible  
     
     
     
     
    Methuselah In The Sky 
     

     
     
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    Tuesday, 31 March 2026

    Lipodystrophy

     



     

    Lipodystrophy refers to a group of disorders characterized by loss (partial or complete) of adipose tissue, often associated with metabolic abnormalities.

     Early Description (19th Century)

    • First clearly described by Mitchell Henry in 1885
    • Reported patients with:
      • Marked loss of body fat
      • Prominent musculature
    • Initially considered a rare constitutional disorder
    •   1885 – Mitchell Henry: first description
    •  1906–1911 – Barraquer & Simons: partial lipodystrophy
    •  1954–1959 – Berardinelli & Seip: congenital generalized form
    • 1990s – HIV-associated lipodystrophy recognized
    •   2000s – Genetic and hormonal basis established  

     

     

     

                                                                Liodystrophy = Leptin Deficiency

     
     
     
     
    Leptin For Lipodystrophy
     
    Approved by U.S. Food and Drug Administration in 2014 for generalized lipodystrophy
     

     “Metreleptin, a recombinant leptin analog, is used to treat generalized lipodystrophy by improving insulin resistance, hypertriglyceridemia, and fatty liver.”

     

     

     


     
     
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