Gerstmann Syndrome

 

The angular gyrus is an important cortical region of the brain located in the inferior parietal lobule. It plays a major role in language, reading, writing, number processing, and spatial cognition. 

Situated in the parietal lobe of the cerebral cortex. 

                        Two Main Functions Include: Language And Mathematics 

                                  Language processing/ Mathematical processing

1. Language processing

   • Important for reading and comprehension

2. Mathematical processing

   • Involved in number understanding and calculation.

 

 

 

 

 

 

Lesion Of Angular Gyrus

 

Gerstmann Syndrome  

 

The syndrome was first described by Josef Gerstmann, who was a neurologist associated with the Vienna School of Neurology.

• Gerstmann studied and worked at the Medical Faculty of the University of Vienna (today the Medical University of Vienna).

• His clinical observations were based on patients treated in Viennese hospitals and neurological clinics

  

 

 

 

 

 

Gerstmann Syndrome 

 

By 1930, Gerstmann formally described the classic tetrad:

1. Agraphia

2. Acalculia

3. Finger agnosia

4. Left–right disorientation

This syndrome became a landmark in neuropsychology and cortical localization studies.

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ACALCULIA  

 

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Primodos

                                                                             Primodos 

 

                          

 

 

•   Primodos contained high doses of synthetic hormones:

  • Norethisterone (a progestogen)

  • Ethinylestradiol (an estrogen)

• It was produced by Schering AG.

   

Principle

It worked as a hormonal pregnancy test:

• A woman took two tablets.

• If withdrawal bleeding occurred → not pregnant.

• If no bleeding → pregnancy likely.

This method relied on hormonal responses rather than detecting hCG like modern tests

 

                                                             Primodos: Suspected Teratogen  

                                   

 

In the 1960s, some doctors suspected a link between Primodos and congenital abnormalities, including:

• limb defects
• heart defects
• brain malformations

One of the early doctors who raised concerns was Isabel Gal in 1967.

Primodos was a 1950s hormone pregnancy test containing norethisterone and ethinylestradiol, produced by Schering AG, later withdrawn due to concerns about possible birth defects. 

 

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International Day Of Women Judges

 

     

 

 

 

 

First Female Judge Of India

 

 

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Ceres

                                         

                                   Ceres — Named after the Roman goddess of agriculture

 

 

Ceres is historically regarded as the first asteroid ever discovered 

 

 It was found on January 1, 1801 

 

Italian astronomer Giuseppe Piazzi 

 

 

 

 

Ceres is not a simple rocky asteroid; it is a water-rich dwarf planet with rock, ice, salts, and organic compounds, making it one of the most chemically complex bodies in the asteroid belt. 

 

 

 

 

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