Warts and Holy Bible

  

                                                                  Human Papillomavirus

 

 

 

Modern Timeline Of Human Papiilloma Virus 

 

 

HPV and Warts  

 

 

 

HPV and  Warts

 

 

 

 

Warts and the Holy Bible 

 

Leviticus 22:22  

 

 

 

 

 

 

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Ringertz Tumour

 

                                                                 Human Papillomavirus  

 

 

 

 

 

 HPV Induced Lesions 

 

 

 

 

    HPV And  Inverted Pailloma aka Ringertz Tumor

  

The tumour was described by Swedish pathologist Nils Ringertz in 1938.

He reported a peculiar sinonasal tumour in which the epithelium grew inward (inverted) into the underlying stroma rather than outward like typical papillomas. Because of his detailed description, inverted papilloma was historically called Ringertz tumour.

 

 

 

 

 

  

 

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Sexually Transmitted Disease Causing Cancer

 

                                                              Human Papillomavirus (HPV)

 

 

                                                                                HPV

                                              Sexually Transmitted Disease Causing Cancer 

 

 

 

                                                                          Current Events

                                                              International HPV Awareness Day

                                      

 

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Ob Gene

 

Scientist: Douglas Coleman
Institution: Jackson Laboratory
Period: 1960s

Two types of genetically obese mice were studied:

• ob/ob mouse → Obese due to mutation in the ob gene

• db/db mouse → Obese due to mutation in the receptor

 

 

 

 

 

 

 Dr. Jeffrey Friedman and Ob Gene 

 

 

 

 

 

The Ob (obesity) gene is the gene responsible for producing the hormone leptin, which regulates appetite and body weight.

 Discovery

• Discovered in 1994 by Jeffrey M. Friedman and colleagues at Rockefeller University.

• Identified while studying genetically obese mice (ob/ob mice).

   

  The Ob gene, also called the leptin (LEP) gene, is located on:

• Chromosome 7

• Long arm (q)

• Region 7q31.3 

                                                              Cytogenetic location: 7q31.3 

   
   
   

• The Ob gene encodes leptin, a hormone secreted by adipose (fat) tissue.

  Leptin acts on the hypothalamus to:

• Suppress appetite

• Increase energy expenditure

• Regulate body weight

   
   
  Mutation of the Ob gene → leptin deficiency → severe obesity. 
   
   
  

  Most common obesity in humans is Leptin resistance
   
  

  
   
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Fatty Acid Metabolism

 

Feodor Lynen (1911–1979) was a German biochemist who made fundamental discoveries in cholesterol and fatty acid metabolism. Spent most of his career at the University of Munich (Ludwig Maximilian University).

 Lynen discovered the key role of coenzyme A (CoA) and acetyl-CoA in metabolism and clarified steps involving HMG-CoA.  

 

 

            His work laid the foundation for modern lipid biochemistry  

 

 

 

 

 He shared the 1964 Nobel Prize in Physiology or Medicine with Konrad Bloch for elucidating the biochemical pathways of cholesterol and fatty acid synthesis.

 

 

 

 

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University Of Munich = Fatty Acid Metabolism