Scream 7

 

 

 

 

 

 

 

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Hamnet

 

 

 

 

 

 

 

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Electrocochleography

 

                                                                        Auditory Pathway

 

Electrocochleography (ECoG) is a diagnostic technique used to record electrical potentials generated in the inner ear (cochlea) and auditory nerve in response to sound stimulation. It has played an important role in understanding cochlear physiology 

 

 

The origins of ECoG trace back to the pioneering work of Hallowell Davis and Saul B. G. T. Derbyshire in the 1930s.

• In 1935, they recorded the cochlear microphonic (CM) from animal models.

• Their work demonstrated that the cochlea produces electrical potentials that mirror acoustic stimuli.

• These discoveries confirmed that hearing involves measurable bioelectrical activity.

   

   
  
   
  Measuring Bioelectric Activity 
   
   
  

  
   
   
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Tennis Elbow

 

                                           Lateral Epicondyle: Distal End Of Humerus

 

 

 

Muscles Originating From Lateral Epicondyle Of Humerus 

 

 

 

 

 

Tennis Elbow aka Lateral Epicondylitis

 

In 1882, British surgeon Henry Morris used the term “Lawn Tennis Arm”, linking the condition to tennis players. 

 

 

 

 

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World Tennis Day

 

1st Monday Of March 

 

In 1873, Walter Clopton Wingfield patented a game called Sphairistikè, played on grass.

In 1877, the first Wimbledon Championships was held — the oldest tennis tournament in the world.

 

 

 

 

 

 

 

 

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Lacosamide

 

Lacosamide was first discovered in 1996 at the University of Houston.

The work was led by Dr. Harold Kohn, Ph.D., a medicinal chemistry researcher at the University of Houston 

 

 

Researchers there hypothesized that modified amino acids might have therapeutic potential for epilepsy and synthesized hundreds of such compounds. 

One of these — originally labeled with codes like ADD 234037/MSP-927 — showed strong anticonvulsant activity in animal models. This compound later became known as lacosamide

 

 

                               Enantiomer Of Amino Acid L - Serine: Anticonvulsant 

                                           

 

 

  

 

Lacosamide

 

Mechanism Of Action 

 

 

 

 

 

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