Sunday, 19 April 2026

Roberstson Cooked Meat Medium

 

                                                                 Clostridium Perfringens  

 
 
 
 Robertson Cooked Meat Medium 
 
 Robertson’s cooked meat medium (liver variant) is a modification of the standard RCM where liver tissue (usually ox/sheep liver) replaces the usual beef muscle.

What’s different about the liver medium?

  • Uses cooked liver pieces instead of muscle
  • Liver is richer in:
    • Iron
    • Vitamins (especially B-complex)
    • Growth factors

The liver version provides an even more supportive environment for fastidious anaerobes, particularly toxin-producing species like:

  • Clostridium perfringens
  • Clostridium botulinum
 
 
 
 
 
 
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Obeticholic Acid

 


Obeticholic acid (OCA) is a semi-synthetic derivative of Chenodeoxycholic acid.

It was chemically modified (6α-ethyl substitution) to make it a much more potent FXR agonist—about 100 times stronger than natural bile acids.

  Obeticholic Acid reduces Intrahepatic fat accumlation, inflammation and liver fibrosis

                                          Obeticholic Acid: Reduces Liver Fibrosis 


 

 
 
 
 
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Alcohol And Liver

 

                                                                       Alcohol And Liver  

 
 
  
Effects Of Alcohol
 
 
 

 
 
 
 
 
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Erythropoiesis In Liver

 

                                                                    Erythropoiesis 

                                                           Liver And Spleen : 6 Weeks  

 

 
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Coinauds Liver

 


                                                                        Claude Coinaud



Claude Couinaud (1922–2008) was a French anatomist and surgeon best known for describing the segmental anatomy of the liver, which revolutionized hepatobiliary surgery.

Couinaud Classification of the Liver

  • Divided the liver into 8 functionally independent segments (I–VIII)
  • Each segment has:
    • Its own portal vein, hepatic artery, and bile duct
    • Independent vascular inflow and outflow
  • This made precise surgical removal (segmentectomy) possible without damaging the rest of the liver
  • Forms the basis of:
    • Modern liver surgery
    • Radiological reporting (CT/MRI)
    • Tumor localization (e.g., hepatocellular carcinoma)  

                                                                     



 
 
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