Nobel Prize, 1990
Physiology/Medicine
Organ And Cell Transplantation In Treatment Of Human Disease
Joseph Murray
Joseph E. Murray (1919–2012)
- Field: Plastic and reconstructive surgery.
- Key
Achievement:
- Performed
the world’s first successful human kidney transplant in 1954
between identical twins (Richard and Ronald Herrick) at the Peter Bent
Brigham Hospital, Boston.
- Developed
surgical techniques and immunosuppressive protocols to prevent rejection.
- Impact:
Opened the door for transplantation of kidneys from genetically
non-identical donors.
E. Donnall Thomas (1920–2012)
- Field:
Hematology and oncology.
- Key
Achievement:
- Developed
bone marrow transplantation as a treatment for leukemia and other
blood disorders.
- Overcame
early challenges of graft rejection and infection.
- Impact:
Bone marrow (hematopoietic stem cell) transplantation became a standard
treatment for many cancers and immune disorders.
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