Cocaine
Medical Complications Of Cocaine
Post Mortem Findings
Cocaine
Autopsy Features
There are no specific findings at autopsy, except for nasal septal ulceration and perforation if the deceased had been a long-term abuser of cocaine. Histological study of nasal septal mucosa in such cases may reveal characteristic changes including arteriolar thickening, increased perivascular deposition of collagen and glycoprotein, and chronic inflammatory cellular infiltration.
Histopathology of heart may
demonstrate microfocal lymphocytic infiltrates, acute coronary thrombosis,
early coagulation necrosis of myocardial fibres, and non atherosclerotic
coronary obstruction due to intimal proliferation.
Cocaine
can be recovered by sampling from recent injection sites, or by swabs from the
nasal mucosa. It can also be recovered from the liver and especially brain,
where cocaine may be found not only in dopamine-rich areas such as caudate,
putamen, and nucleus accumbens.
Cocaine: Myocardial Infarction
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Snapshot
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