Cardiac Poison

 

                                                                         Cardiac Poison  

 

 

 

 Aconite 

 

Toxicity: One of the most poisonous plants known; contains alkaloids like aconitine, which are potent neurotoxins and cardiotoxins.

Mechanism: Aconitine binds to voltage-gated sodium channels in nerves and cardiac tissue, keeping them open → persistent depolarization → arrhythmias, paralysis, and death.

 

 

 

 

 

 

Poisonings Throughout History: George Henry Lansom

Lamson was put on trial for murder in March 1882 and was found guilty based on evidence that he purchased the poison – aconite

 

 

 

 

 

 

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