Hypothalamus And Hunger

                                                              Dr. Bharat Kumar Anand

 Known as the father of modern physiology in India.Played a key role in establishing AIIMS Delhi as a premier medical research institution.Awarded numerous honors, including the Padma Shri.

Dr. Bharat Kumar Anand, a pioneering Indian physiologist, made landmark contributions to our understanding of hunger regulation by the hypothalamus in the mid-20th century. His work, alongside Dr. John R. Brobeck, provided foundational insights into how the brain controls feeding behavior.

In 1951, B.K. Anand and J.R. Brobeck published a seminal paper demonstrating that:

Lesions (damage) to the lateral hypothalamus in rats caused complete loss of hunger, leading to aphagia (refusal to eat).

This led to the identification of the lateral hypothalamus as the "feeding center" of the brain.

Current Events 

Snapshot

From these studies, the "Dual Center Hypothesis" of hunger was developed:

1. Lateral Hypothalamus (LH) → Feeding center (stimulates hunger)

2. Ventromedial Hypothalamus (VMH) → Satiety center (signals fullness)