University Of Michigan
In the late 1960s, University of Michigan researchers conducted experiments in which monkeys were given access to caffeine, cocaine, morphine, mescaline, amphetamines, barbiturates, and other substances to study drug-seeking and dependency behaviors. Some monkeys self‑administered drugs via intravenous setups.
RESULTS
|
Drug |
Observed
Monkey Behavior |
|
Cocaine |
Monkeys repeatedly
self-injected to the point of extreme agitation and self-harm,
including violent behavior and physical injuries. |
|
Morphine |
Monkeys
showed strong addiction, preferring morphine over food or water. Some
would overdose voluntarily. |
|
Amphetamines |
Induced paranoia,
aggression, and sleep deprivation. Monkeys became increasingly
irrational. |
|
Barbiturates |
Led to sedation
and eventual physical dependence. Sudden withdrawal caused seizures and
death in some cases. |
|
Mescaline
(hallucinogen) |
Monkeys
behaved erratically, hallucinated, and attempted to escape. Some would
refuse repeated self-dosing. |
|
Caffeine |
Minimal
addictive behavior. Sporadic self-administration, often rejected after
a few doses. |
|
Alcohol |
Results
were mixed—some monkeys showed preference while others refused it; binge
behavior was observed in some cases. |
|
Feature |
Detail |
|
Genetic
Similarity to Humans |
~98.7% of DNA is identical
to humans (Homo sapiens) |
|
Chromosome Number |
48 chromosomes
(humans have 46 due to a fusion of two ancestral ape chromosomes) |
|
Genome Size |
~3.3 billion base
pairs (very close to humans) |
|
First Sequenced |
2005 (chimp genome completed by the Chimpanzee Sequencing and Analysis Consortium) |


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