Normal Sperm
The discovery of CatSper (Cation channel of sperm) is relatively recent and came from research on sperm motility and male infertility in the late 20th–early 21st century.
CatSper (Cation channel of Sperm) is a special calcium ion channel found in the tail (flagellum) of spermatozoa.
CatSper channels allow Ca²⁺ (calcium ions) to enter the sperm, which is required for:
- Sperm motility (movement)
- Hyperactivation (strong tail movement needed to reach the egg)
- Fertilization ability
- Acrosome reaction
Sperm Motility
CatSper
Intact CatSper = Fertilization






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