The Incans used bismuth in bronze alloys as early as the 15th century, long before it was properly identified in Europe.
In medieval Europe, bismuth was used by alchemists, who referred to it under various names such as “Wismut” (German for "white mass" or "white metal").
Bismuth saw growing industrial use in the 19th
and 20th centuries, especially in low-melting alloys and cosmetics.
Because of its low toxicity, it has
replaced lead in many applications, such as:
- Pepto-Bismol (bismuth subsalicylate,
used for gastrointestinal relief),
- Cosmetics (like pearl powders),
- Fire
safety devices (due
to its low melting point).
Pepto-Bismol
.jpeg)
1900s (Early):
Pepto-Bismol originated as a treatment for infants with cholera infantum,
a dangerous gastrointestinal illness causing severe diarrhea and dehydration.
It was originally called "Bismosal" and was developed by a doctor in the United States working with a pharmaceutical company.
Development: A doctor in New York City, the specifics of whom are not explicitly mentioned, developed a formula in his home that included pepsin, zinc salts, salol, oil of wintergreen, and a pink coloring agent. This formula was originally marketed as "Mixture Cholera Infantum".
1901 – Norwich Pharmacal Company:
The Norwich Pharmacal Company (Norwich, New
York) introduced Bismosal, which contained bismuth subsalicylate, along with
flavorings and other soothing agents.
.jpeg)
It was marketed as a pink-colored,
pleasant-tasting liquid for stomach relief, particularly effective in treating
diarrhea, upset stomach, and nausea.
1919 – Rebranded as Pepto-Bismol:
To broaden its appeal and commercial
viability, Bismosal was rebranded as Pepto-Bismol:
- “Pepto”
derived from "peptic" (relating to digestion)
- “Bismol”
from bismuth, its active ingredient
Pepto-Bismol: Black Tongue
.jpeg)
.jpg)
No comments:
Post a Comment