Richard Pffeifer
Richard Pfeiffer: Isolated A Bacterium From Flu Patients
1892: Discovery Of Hemophlus Influenze Type B
1975: Vaccine For Hemophilus Influenze Type B
Vaccine For Hemophilus Influenze Type B Meningitis
1996 Lasker Award
Richard Pffeifer
Porter W. Anderson Jr. and David Hamilton Smith were two of the four scientists principally responsible for developing the Haemophilus influenzae type b (Hib) vaccine. Their work transformed Hib from a leading cause of childhood meningitis into a largely vaccine-preventable disease
Their research began in the late 1960s at Boston Children's Hospital, where they investigated why Hib caused severe infections in infants and young children. Anderson, a microbiologist, and Smith, a pediatric infectious disease specialist, identified the bacterium's capsular polysaccharide—polyribosylribitol phosphate (PRP)—as the critical antigen capable of inducing protective immunity.
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