~400 BCE – Hippocrates
The Greek physician Hippocrates was among the first to describe stroke-like symptoms. He used the term “apoplexy” (from the Greek apoplēxia, meaning “struck down with violence”) to describe a sudden loss of consciousness and paralysis.
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He recognized that the condition was abrupt and often fatal, though its internal cause remained unknown.
Rudolf Virchow (1856) described thrombosis and embolism, explaining how blood clots travel and block cerebral arteries — foundational for modern stroke mechanisms Terms like “cerebral infarction” and “cerebral hemorrhage” began replacing “apoplexy.”
Timeline Of Stroke
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