Necroptosis

 

                                                                             Necroptosis  

 

 

 

 

Discovery Of Necroptosis 

 

A major breakthrough occurred in 2005, when Alexei Degterev and colleagues, working with Junying Yuan, described a small molecule called Necrostatin-1. This compound inhibited a specific type of necrotic cell death. Crucially, they showed that the process was regulated rather than accidental, and linked it to a kinase called RIPK1. This study effectively established necroptosis as a distinct, programmed pathway. 

 

 

 

 

 

 Necroptosis

 

 

 

 

Mechanism Of Necroptosis

 

 

 

 

 

Apoptosis VS Necroptosis 

 

 

 

Necroptosis In Pathology

 

 

 

 

 

Pathology: Ischemic Reperfusion Injury (Necroptosis) 

 

 

 

 

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