Discovery of nitric oxide in exhaled breath
In 1991, Lars Gustafsson and colleagues made a pivotal observation:
They detected nitric oxide in exhaled human breath.
This finding was groundbreaking because:
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It showed that NO is produced within the respiratory tract
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It suggested a potential non-invasive biomarker of airway biology
Modern perspective
Today, FeNO is recognized as:
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A non-invasive inflammatory biomarker for Airway Inflammation
It Can Be Used For Diagnosis Of
Snapshot
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