Sedate

Ibn Zuhr: First to test medicines on Animals and then give it to Humans 

Ibn Zuhr wrote the First manual on Therapeutics

Ibn Zuhr Pharmacopoeia was the first Arabic book to be printed as a movable

Pharmaceutical Literature 

Europeans gets inspired from Arabs

Official Pharmacopoeia 

Valerius Cordus a German Physician compiled the 1st Official Pharmacopoeia 

Valerius Cordus is credited for the Synthesis of Ether 

Valerius Cordus a German Physician synthesizing Ether

William TG Morton a American Dentist made the first public demonstration of 

Ether 

Ether an anesthetic to Skeletal Muscle Relaxants 

Jungles To Operation Theatre

D Tubocurarine 

Tubocurarine: First Muscle Relaxant To Be Used Clinically

D-Tubocurarine To Other Skeletal Muscle Relaxants

History Of Neuromuscular Blocking Agents

First Synthetic Neuromuscular Blocking Agent 

Gallamine 

Flaxedil (Gallamine) : First Synthetic Neuromuscular Blocking Agents

The first NMBA used for modern medicine, d-tubocurarine, was a non-depolarizing agent. 

Introduced in 1942, it is the active principle of Curare.

It was extracted from certain plants native to South America.

Pharmacologist Daniel Bovet, DSci, ForMenRS  (1907-1992) was born in Switzerland. He spent his career in France and Italy. 

 In 1946, he and his colleagues at the Pasteur Institute in Paris synthesized Gallamine

Gallamine (Flaxedil), the first synthetic NMBA.  

A non-depolarizing agent, it is only one fifth as potent as d-tubocurarine.  It has a side effect of increasing heart rate.  This package of Flaxedil was made by Davis & Geck in the early 1950s. 

Daniel Bovet: D Tubocurarine To Gallamine 

Nobel Prize 1957: Gallamine 

1946: Gallamine by Dr Daniel Bovet

1949: Succinyl Choline by Dr Daniel Bovet 

Skeletal Muscle Relaxants

Gallamine is a longer acting Skeletal Muscle Relaxant 

Current Events

PM Narendra Modi says India will extend coronavirus lockdown until 3 May

India's Prime Minister Narendra Modi has extended a nationwide lockdown until 3 May to contain the spread of the coronavirus.

India has reported 8,988 active cases and 339 deaths so far.

                                                                   Snapshot

                                                           1 st Pharmacopoeia

Ether: 1 st Official Pharmacopoeia

Ether To D Tubocurarine To Gallamine