Tachyphylaxis

Drug Dose: Source of Variability: Tachyphylaxis 

Doses of  a drug  repeated in quick succession 

Result in marked reduction in response

Snapshot

Tachyphylaxis: Depletion of receptors for the drug

Depletion of neurotransmitters to bind to receptors

Delilah has weak, poor receptors for the drug developing in rapid Tachyphylaxis