Wednesday, 12 September 2018

Basal Nucleus Of Meynert



The Cholinergic System 

Neurons from this system release Acetyl Choline 

System has 3 cores: MSN/BNM/PC

Medial Septate Nucleus projects to the Hippocampus

Basal nucleus of Meynert projects to Cerebral Cortex

Pontomesencephalotegemtal complex project to Thalamus 



Acetyl Choline Pathway





Role of Acetylcholine in the CNS 

Acetylcholine in CNS : Memory/Arousal/Attention 


The primary cholinergic input to the cerebral cortex comes from the 

Basal Nucleus Of Meynert





Alzheimers Disease: Cholinergic system is most affected 

90 % of cells in the nucleus Basalis Of Meynert are destroyed in 

Alzheimer's Disease



Neurotransmitters and Pathology




Snapshot














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