The Cholinergic System
Neurons from this system release Acetyl Choline
System has 3 cores: MSN/BNM/PC
Medial Septate Nucleus projects to the Hippocampus
Basal nucleus of Meynert projects to Cerebral Cortex
Pontomesencephalotegemtal complex project to Thalamus
Acetyl Choline Pathway
Role of Acetylcholine in the CNS
Acetylcholine in CNS : Memory/Arousal/Attention
The primary cholinergic input to the cerebral cortex comes from the
Basal Nucleus Of Meynert
Alzheimers Disease: Cholinergic system is most affected
90 % of cells in the nucleus Basalis Of Meynert are destroyed in
Alzheimer's Disease
Neurotransmitters and Pathology
Snapshot
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