Notochord

Notochord stimulates Neural tube formation 

Neural tube formation in turn stimulates the development of the 

Vertebral Column  from Somites 

Vertebral Columm: Derived form sclerotomes of somites

Sclerotome: Cranial, Middle and Caudal 

Vertebrae: Caudal part of sclerotome+Cranial part of next sclerotome

Middle part of Sclerotome: Intervertebral disc 

Notochord: Basis of axial skeleton (Bones of head and vertebral columm)

Notochord: Organiser of nervous system function

Fate Of Notochord

Notochord located in the vertebra undergo degeneration and disappear 

The ones located in between undergo mucoid degeneration to form 

Nucleus Pulposus (Remanant of  Notochord)

Notochord To Nucleus Pulposus

Intervertebral Disc: Annulus Fibrosus and Nucleus Pulposus

Ligaments of the Spine

Disc Herniation

Notochord organiser of Neural development can end  up in Herniation of Disc

Common cause of Sciatica: Bulging and Herniated disc

Notochord

Primitive Beginning to the Backbone

Notochord To Neural Development