Teriparatide

                                                 Distribution and Function of Calcium

 

 

 

                                                 Parathyroid Gland: Homeostasis Of Calcium

 

 

 

 Parathyroid Hormone: Actions 

 

 

Parathyroid Hormone To Teriparatide 

Teriparatide aka Recombinant Human Parathyroid Hormone

 

 

 

Teriparatide is a recombinant protein consisting of the first 34 amino acids of parathyroid hormone. This drug was developed after the serendipitous discovery in rats that PTH administered continuously resulted in increased bone resorption and bone loss, whereas PTH administered by a daily injection had an anabolic effect, with increases in both resorption and formation, favoring the latter. In these rats the bone mass was markedly greater than in control.

 

Teriparatide is a recombinant form of N-terminally truncated and 34-amino acid-containing human parathyroid hormone (1–34). It is marketed by Eli Lilly under the brand name Forteo. It is prescribed as an anabolic agent  indicated for use in postmenopausal women  with osteoporosis.

 

 

Teriparatide 

 

 

 

 

 

 

 

 

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