Saturday 10 September 2022

Philanthotoxin

 


 Beewolf paralyzing its prey
 

 
Beewolf To Philanthotoxin 433 
 
PhTX-433 was structurally elucidated and synthesized in 1988 by Eldefrawi and colleagues. For the isolation and structural identification of PhTX-433 female wasp venom glands were fractionated

 
 
 
 
 

Philanthotoxin 433 
 
Philanthotoxins reversibly inhibit AMPA (also called the "quisqualate receptor"), kainate, and NMDA ionotropic glutamate receptors (iGluRs)
 

 
 
 
 
Philanthotoxin: Block Nicotinic Acetylcholine  Receptors
 

 

 
 
 
Snapshot 
 
 




Philanthotoxin: Glutamate Antagonist
 


 

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