Tuesday 7 May 2019

Synaptic Potential



Neuron terminates at muscle, gland or another neuron 

Junction between two neurons is called a Synapse 


Synapses: Electrical and Chemical Synapses



Electrical Synapses: Two neurons are connected by gap junctions 

Gap junctions allow charged particles to flow between cells
Chemical Synapses : Most Common Type 



Presynaptic Terminal - Synaptic Cleft - Post Synaptic Membrane 






Neurotransmitters In Chemical Synapse 

Postsynaptic Potential

Neurotransmitter receptors mediate changes in membrane potential

2 Postsynaptic Potentials: EPSP and IPSP 


Eg: EPSP



EPSP: Excitatory (Depolarisation)







EPSP  and IPSP are graded potential

They can be summated 


Temporal Summation 


Spatial Summation 






Post synaptic potential is a Graded Potential



Graded Potential VS Action Potential

Graded potential depending on the initial stimulus can be summed 

Action Potential: All or none phenomenon cannot be summed 





Synpatic Potential Recording 






Nobel Prize: Nerve Membrane Physiology




Snapshot











































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