Friday 17 May 2019

Alluminium Phosphide aka Rice Tablets




Aluminium Phosphide aka Rice Tablets 






First known case of Alluminium Phosphide poisoning occured in Bangladesh

Died 8 days after ingestion of a Single Pellet



Alluminium Phosphide: Mode Of Poisoning

Ingestion: Fatal Dose 1-3 Tablets 

Inhalation: 400-600 ppm (Fatal Dose). Majority die in the first 24 hours




Effect Of Phosphine Gas Inhalation On Health 

500 ppm inhalation: Death after 45 minutes 




Mechanism Of Action: 

Inhibits Respiratory Chain Enzymes 

Inhibits Electron Transport/Inhibits Cytochrome Oxidase 



Signs and Symptoms 

Inhalation Of Phosphine Gas 



No Antidote available for Aluminium Phosphide poisoning

Treatment Is Supportive 




Medical Importance In India 

Suicidal Agent  In Rural India 





Current Events 


Bizarre! Woman dies after her mouth explodes during treatment in Aligarh hospital; 

doctors puzzled


Aligarh: In a rather strange incident, a woman in Uttar Pradesh's Aligarh died following an explosion in her mouth while she was being given treatment at a local hospital. As per reports, the woman had been rushed to the JN Medical College (JNMC) in Aligarh on Wednesday evening after she had purportedly consumed poison.
"There could be a possibility that she allegedly consumed Celphos tablet (Aluminium phosphate) which release phosphine gas in addition to Aluminium Oxide and other gases (which are highly inflammable) and the explosion occurred when it came in contact with gastric acid."
Dr Zaidi alleged that it was perhaps the first time in medical history when such a case has taken place








                             



























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