Wednesday 6 March 2019

Antibiotic


Discovery of Penicillin paved the way in study of Soil Microorganisms

Selman Waksman was engaged in the study of Soil Microorganisms

1939: Student of Selman Waksman discovers the first soil based antibiotic

First soil based antibiotic was found to be too toxic for Humans


Waksman inspired by the discovery and with support of Merck started working on

 Antibiotic


Term Antibiotic was first coined by Selman Waksman in 1942 


Streptomycin: First drug to be known as a Antibiotic

Streptomycin was isolated on October 1943 by Waksman Lab


Streptomycin was tried on animals infected with TB

Animals infected with TB responded to Streptomycin well


Animals To People

Patricia T:  Streptomycin first success against TB 

August 1945: Streptomycin appears to be a Miracle Cure 



Streptomycin: Worlds First Randomised Curative Trial


Results of RCT trial show efficacy against TB 

US Patent Office issues a patent to Streptomycin in 1948

Merck then starts mass production of Streptomycin 


Post Mass Production: Streptomycin a perfect cure for TB




Current Events

Antibiotics Stopping Microbes

                                 Putin says Russia stopped nearly 600 spies last year

Moscow (CNN)Russian President Vladimir Putin said Wednesday that the country's security services stopped nearly 600 foreign agents and intelligence personnel last year, declaring that adversaries were trying to interfere in Russia's domestic affairs.

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