Snake Venom
Snake Venom To Nerve Growth Factor
Rita Levi - Montalcini: Discovery Of Nerve Growth Factors
Snake venom played central role in the identification of nerve growth
factor (NGF) by Stanley Cohen and Rita Levi-Montalcini, who shared the
1986 Nobel Prize for their work. They discovered
that the venom of the moccasin snake (a species of pit viper from the
Southeastern US) was a rich source of a factor that could induce
outgrowth of fibers from cultured neurons. This enabled them to
characterize and eventually purify NGF, the first growth factor to be
identified and the prototype for a large family of signaling molecules.
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