CYP19A1

Two Cell Gonadotropin Theory

Granulosa Cells Of Ovary 

Aromatase Enzyme: Conversion Of Androgen To Estrogen

Granulosa Cells Of Ovary To Brain 

Gene in the brain of men controls sex drive, study finds

An enzyme has been found in the brain of men which is responsible for sex drive.

A study from Northwestern University investigated the role of aromatase in the organ and found the enzyme converts testosterone into oestrogen. 

These hormones are known as the male and female sex hormones, respectively, but creating oestrogen is crucial for male sexual function. 

It is needed in high levels to drive libido and is essential for erectile function. Without oestrogen being made from testosterone, a man’s sex drive plummets. 

Researchers also found aromatase is produced by a single gene, called Cyp19a1, opening up potential routes to target the enzyme.

                                                                               

Snapshot 

The biologically active estrogen estradiol has important roles in adult brain physiology and sexual behavior. A single gene, Cyp19a1, encodes aromatase, the enzyme that catalyzes the conversion of testosterone to estradiol in the testis and brain of male.

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