Monday, 6 September 2021

Cocaine

 


Nerve



Nerve Cell Membrane: Voltage Gated Ion Channels 

Voltage Gated Sodium Channel: M and H gate 



Voltage Gated K channel




Propogation of Action Potential 




Cocaine

The First Local Anesthetic 

Introduced first to Clinical Opthalmology as Ocular Anesthetic


First Effective and widely used Local Anesthetic: Procaine 



Mechanism Of Action: Local Anesthetics

Inactiation Of Voltage Gated Sodium Channels 

Closure Of H gates 




Snapshot





Drugs That Work On You Work On Me 




































M gate 































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