Thursday, 31 December 2020

Hit The Histone With Stones


Histones 








Histone undergoes Phosphorylation/Acetylation/Methylation/Ubiquitination






Histone Acetyation/Deacetylation


Histone Acetylation: Gene Transcription 

Histone Deacetylation: Gene Silencing 





Histone Acetylation: Gene Transcription 




Histone Deacetylation: Gene Silencing 

Histone Deacetylation overexpressed in most Cancers

Histone Deacetylation: Silencing Of Guardian Proteins 

In Contrast Histone Methylation increases Tumour suppressor proteins p53/p21

Histone Methylation: Increases cell cycle check points 




Histone Acetylation/Deacetylation 






Histone Deacetylase Inhibitors









Histone Deacetylase Inhibitors In Esophageal Cancer 






Histone Deacetylase Inhibitors Market 





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