Friday, 11 September 2020

Coumarin and Blood Thinning



Cinnamic Acid To Dicoumarol To Warfarin 




Coumarin In Damaged Sweet Clover is converted to Dicoumarin 

1920: Sweet Clover containing Dicoumarin causes fatal bleeding in cattle 

1944: Synthesis of Warfarin 







1952: Use as a Rodenticide 



1954: Clinical Use 

Warfarin: First Anticoagulant approved in the World in 1954





Warfarin: Mechanism Of Action 





Snapshot 






























 

No comments:

Post a Comment