We owe much of our current understanding and treatment of pain to many scientists, clinicians, and philosophers in the past centuries. From René Descartes' origin of the Specificity Theory of Pain to Dr. Ronald Melzack and Dr. Patrick Wall's Gate-control Theory of Pain (GCT), pain science and treatment has been redefined and reframed many times in the past 350 years. Melzack and Wall's GCT shed much light in our understanding of pain, which opened doors to new research since the late 1960s. Having withstood over 50 years of tests and rigors of science, the GCT helped Melzack and his colleagues develop the Neuromatrix Theory of Pain, which is based on their work with patients experiencing phantom-limb pain. Pain Timeline
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