Man is made up of Collagen
Collagen: The most abundant body protein. Makes up 30 % of all proteins
Ligaments 70 % connecting muscle to Bone - 90 % and covered by Skin 70 %
Collagen is like steel rods reinforced to concrete
Collagen content in our body declines by age
Lack of collagen in ageing skin
Visualizing Collagen
STAINS
Mason Trichrome to visualise Collagen
Trichrome Stain created by H Gibbs in 1880
To differentiate between collagen and smooth muscle in slide
Mason Trichrome Stain is used commonly for Alcoholic Cirrhosis
Mason Trichrome: Hypertrophic Cardiomyopathy
Mason Trichrome and Collagen Density
Collagen
Collagen is like steel rods reinforced to concrete
Collage
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