Wednesday, 29 March 2023

Prussian Blue

 

 


 

 

                                                                        History Of Blue

 




                                                              18 th Century: Prussian Blue 

                                                            Modern Synthetic Pigment Dye 


 
 Around 1706 Diesbach was working in the laboratory of Johann Conrad Dippel in Berlin. Using an extract of crushed cochineal insects, iron sulphate and potash to create cochineal red lake, he used potash that was mixed with Dippel"s animal oil. The result was a very pale red which he concentrated to purple, later a deep blue.

While neither Diesbach nor Dippel knew what exactly happened the formula was the first modern Synthetic pigment, and an important invention, because at that time the alternative blue pigments were either not very successful or affordable for large scale use.

The pigment was first mentioned in a letter, the first of several, from Frisch to the president of the Royal Academy of Sciences, Gottfried Wilhelm Leibniz, dated March 1708. By August 1709, the pigment was being referred to as "Preussisch blau" and by November of that year, as "Berlinisch Blau".
 
 
Prussian Blue 
 
 
 
 
 
 
Cyanide was isolated from Cherry Laurel 
 
 
 
Cherry Seeds Contain Cyanide 
 
First Isolated In 1782 
 
 
Other Cyanogenic Glycosides In Plants 
 

 
 
Prussian Blue To Cyanide 

 
 
Toxicokinetics Of Cyanide 
 



 History and Military Use

 
 
 
Cyanide off the Battlefield
 


Poison Chemistry: Cyanide


 Prussian Blue: Antidote To Thallium Poisoning 

 
 
 
Prussian Blue: Radiation Emergency 
 
 
 
 Prussian Blue Staining 
 
 

 
Current Events 
 
 

 

 
Snapshot 
 
 



 



 

Monday, 27 March 2023

King Of Poison To Therapeutics

 

                                                                              Arsenic

 
 
Arsenic Known To Man Since 2500 BC  
 
Bronze Age 
 
 
Discovery Of Arsenic
 
 
Uses Of Arsenic
 
 


 
Arsenic: King Of Poisons
 

 
 
Arsenic Poisoning
 

 
 

 
 
Prevention And Management Of Arsenic Poisoning 
 

 
 
Arsenic As A Poison To Therapeutics 
 

 
 
 
17 th Century: Fowlers Solution 
 

 
 
 1859: Atoxyl: Treatment Of Trypanosomiaisis
 
 
 
 
 
Paul Ehlrich: Magic Bullets 
 
Salvarsan 
 
 
 
 
 
 
 
1957: Discovery Of Acute Promyelocytic Leukemia
 
 
 
 
 
 
1998: Response To Arsenic

 
 
 
 

Arsenic Trioxide: Treatment Of Leukemia
 

 
 
 
 
 
 
 
 
Snapshot