Michael Sveda
In 1937 Michael Sveda a graduate student at the University of Illinois
was working in the lab on the synthesis of anti-fever medication.
One day in the laboratory of Prof. Audrieth, he picked up a cigarette lying on his lab bench, put it in his mouth, and discovered that it tasted surprisingly sweet.
Sveda then tasted every substance in sight and traced the sweetness to a compound known as sodium cyclohexylsulfamate. Five years later, Sveda and his professor obtained a patent and assigned the rights to DuPont, Sveda's new employer.
One day in the laboratory of Prof. Audrieth, he picked up a cigarette lying on his lab bench, put it in his mouth, and discovered that it tasted surprisingly sweet.
Sveda then tasted every substance in sight and traced the sweetness to a compound known as sodium cyclohexylsulfamate. Five years later, Sveda and his professor obtained a patent and assigned the rights to DuPont, Sveda's new employer.
After some initial development by DuPont, cyclamate was taken up (under
licence) by Abbott Laboratories, a pharmaceutical firm in North Chicago
that hope to produce a sweetener suitable for diabetics and other people
on sugar restricted diets.
This substance, which proved to be approximately 30 times sweeter than sugar, was first marketed in 1949 as sodium cyclamate in tablet form for use by diabetics.
This substance, which proved to be approximately 30 times sweeter than sugar, was first marketed in 1949 as sodium cyclamate in tablet form for use by diabetics.
Sodium cyclamate |
In November 1959, cyclamate was place in the Food and Drug
Administration’s list of GRAS. Cyclamate is approved as a sweetener in
at least 130 countries while it is currently banned in the United
States.
Sodium Cyclamate To Cyclohexylamine
Cyclohexylamine = Carcinogen
Cyclamic Acid Carcinogenesis
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