Formalin: Preservation Of Organs
Formalin Blocks Nerve Conduction
In vitro
- At concentrations of 10 mM and higher, formaldehyde can completely block nerve conduction in A and C fibers. At 30 mM, formaldehyde can irreversibly block all A fibers, but some slow C fibers may survive.
- In pilot experiments with rat skin, high concentrations of formaldehyde can transiently excite and then block all sensory nerve endings. This is followed by a second phase of discharge in small Aδ- and C-fibers.
FORMALIN BLOCKS NERVE CONDUCTION
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