Dithranol

 

                                                   Dithranol For Plaque Psoriasis

Dithranol accumulates in Mitochondria where it interferes with the supply of energy to the cell, probably by the oxidation of dithranol releasing FREE RADICALS. This impedes DNA replication and so slows the excessive cell division that occurs in psoriatic plaques. 

                                                 Dithranol Can Burn And Stain The Skin

It temporarily stains the skin a yellowy-brown to purple if not washed off after a period of time (45-60 minutes). It permanently stains clothing fabrics, shower curtains, and other materials such as ceramic sinks the same yellow-brown to purple in color depending on the concentration. It may cause a local burning sensation and irritation.

Snapshot