Sunday, 12 May 2024

Alpha Lipoic Acid

 

                                                                       Lipoic Acid

 Lipoic acid is found in a wide variety of foods from plant and animal sources. Animal tissues with high lipoyllysine content (~1-3 μg/g dry wt) include kidney, heart, and liver, while lipoyllysine-rich vegetables include spinach and broccoli.



Lipoic acid is a sulfur-containing compound that is absorbed from the diet and synthesized in mitochondria (Smith et al., 2004). Upon entering cells, it can be reduced to the dithiol form dihydrolipoic acid by the thioredoxin system (Smith et al., 2004).
 

 
 
 
Mechanism Of Lipoic Acid
 

 
 
 
 
Theory To Practice
 
Alpha Lipoic Acid: Decreases Blood Glucose Level 

Alpha-lipoic acid has been used for years to treat peripheral neuropathy in Germany. However, most of the studies that have found it helps have used intravenous (IV) alpha-lipoic acid. 

 One study did find that taking alpha-lipoic acid for diabetic neuropathy reduced symptoms compared to placebo.

 
 
 
 
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