Glucagon is a peptide hormone that is produced primarily by the alpha cells in the islet of Langerhans in the pancreas, but also in the stomach, intestinal enteroendocrine cells, and some neurons.
Kimball and Murlin identified this substance in the pancreas extracts and named it ‘glucagon’, derived through the words ‘glucose agonist’ (Kimball & Murlin 1923, Muller et al. 2017).
Eli Lilly is credited with the isolation of pure glucagon and the determination of its amino acid sequence (Kimball & Murlin 1923, Staub et al. 1953 Bromer et al. 1957, Muller et al. 2017).
Physiology Of Glucagon
Evolution Of Glucagon
Secretion Of Glucagon
Glucagon In Fasting/Starvation
Snapshot
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