Friday, 28 March 2025

Somatostatin

 

                                                                         Somatostatin

                Discovered in the Hypothalamus in 1973 by Brazeau and Guillemin





Somatostatin is a naturally occurring inhibitory polypeptide hormone first isolated from the sheep hypothalamus (Brazeau et al., 1973). 

It is widely distributed throughout the human central nervous system (CNS) and peripheral tissues. 




Somatostatin In Pancreas



                                                            Actions Of Somatostatin

Somatostatin has a broad range of biological actions that include the regulation of neurotransmission and secretion and the inhibition of the release of growth hormone (GH), thyroid-stimulating hormone (TSH), gastrointestinal (GI) hormones, pancreatic enzymes and neuropeptides (Lamberts, 1988; Schettini, 1991). 







Physiology To Pharmacology

Somatostatin




Somatostatin In Imaging 




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