Camphor: Strong Aromatic Odour On Burning
Camphors burns without leaving ash or residue
Camphor: Solid ketone obtained from volatile oil of Cinnamomum Camphora
Camphor: Physical Degradation
Camphor Degradation: Loss Of Volatile Components
Volatile contents lost at ambient temperature through vaporization
Volatile Components are present in
Alcohol, Ether, Iodine, Volatile Oils, Camphor and Menthol
Loss Of Volatile Components Depends Solely On Potency
Potency: Amount Of Drug required to produce a response
Pure Natural Extracts are more potent than diluted extracts
Thick Cream more potent in flavour in comparison to diluted butter milk
Examples
Pain Killers
10 mg of Piroxicam is more potent than 100 mg of Aspirin
Carfentanil is more potent than Heroin
Clobetsol Propionate (0.05): Superpotent Steroid
Cannabis has got 300 % stronger in 30 years
Pharmaceutical Degradation Affects The Potency Of The Drug
Physical Degradation
Example: Vitamin Tablets
Expired Vitamin Tablets/Capsules = Change In Drug Release
Expired Vitamin Tablets dont have the expected content in them
Other Preparations
Expired Suspension: Loss Of Drug Content Uniformity
Expired Emulsions: Loss of drug content uniformity in doses
Expired Oinments: Loss of drug content uniformity
Apart From Physical There Is Chemical Degradation
Microbial Degradation
Pharmaceuticals
Short term application/effects
Snapshot
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